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Clinical Observation on Palopperidone Sustained
AbstractObjective of this study was to evaluate the efficacy and adverse drug reactions (ADR) of palipeddonesustained release tablet in the treatment of schizophrenia in outpatients. Outpatients withschizophrenia treated with palipeddone sustained release tablet (observation group)in our hospitalfrom Apr. to Sep. in 2009 were followed up and compared with those treated with risperidone (controlgroup) during the same period. PANSS and TESS were applied to evaluate efficacy and ADR. Resultssuggest that the cure rates were 42.4% for control group and 49.6% for observation group. The effectiverates were 74.8% for control group and 80.3% for observation group (P<0.05). As compared withcontrol group, observation group showed slightly ADR with low frequency. In summary palipeddonesustained release tablet which has sound effect on schizophrenia with slightly ADR suits for outpatienttreatment.